Many people (bloggers) are talking about the problem of wp-admin.php page which is not opening when they are trying to reach it.It is giving error 404 page not found.I had also this error but i was able to resolve it by following these steps:
Go to your ftp software mine is flashfxp
Login to your website
Take a back up of your whole website
Now go to top folder’s i.e wp-admin,wpau-backup,wp-content,wp-includes Check their attribute status It might be converted to 757 and files attribute might be 646 which should be 755 and 644 for default.
Change All folders to 755 and all files to 644

Reminding you i am saying about all go through each folder inside your blog there are many of them and try no one is left .

Change also the attribute of all of your files which are outside of these folders like wp-app.php,wp-atom.php etc.
Do it to all
That’s it
This has been time-consuming and ineffective. Thanks anyway.
thanks for your solution,
i have that problem on my blog. Now i can resolve that.
regards
Danang
Thank you for your solution. This resolved the 404 error for wp-admin for our site.
Best,
Jeff
After going through lots of other tips that included updating the .htaccess file, disabling plugins & updating some php file .. and they all didn’t work .. this one solved the problem. Thanks a lot.
Seems to be working..it worked for me. Thanks..contact me if anyone needs help on this.